Pfizer Inc. (NYSE: PFE) announced the suspension of the osteoarthritis clinical program for the investigational compound tanezumab following a request by the U.S. Food and Drug Administration (FDA). The worldwide suspension which is effective immediately follows a small number of reports of tanezumab patients experiencing the worsening of osteoarthritis leading to joint replacement…

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Medtronic, Inc. (NYSE:MDT) announced the launch of KYPHON ActivOs 10 Bone Cement with Hydroxyapatite, a polymethylmethacrylate (PMMA) bone cement containing hydroxyapatite (HA) for use in the treatment of patients with vertebral compression fractures (VCFs) who are undergoing minimally invasive surgery with KYPHON® Balloon Kyphoplasty…

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Enobia Pharma announced positive interim data from a clinical study of ENB-0040, a bone targeted enzyme replacement therapy, under investigation for the treatment of hypophosphatasia (HPP). After 12 weeks of treatment with ENB-0040, children with HPP showed marked improvements in bone mineralization and function including increases in strength, endurance and mobility and reduction in pain…

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Tishya Wren, PhD, of The Saban Research Institute at Childrens Hospital Los Angeles, has received a $2.5 million grant from the National Institutes of Health – National Institute of Child Health and Human Development to study bone development in children with myelomeningocele, the most severe type of spina bifida …

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Rome, 18 June 2010: Lodotra – a unique modified-release formulation designed to be taken before bed and release low-dose prednisone in the early hours when inflammatory cytokines peak – achieves clinically significant improvements in ACR20, morning stiffness and pain in patients with rheumatoid arthritis (RA), according to results from clinical trials presented at the 11th [...] Read more »

The 2010 FIFA World Cup™ brings the biggest fans and the best soccer players together for an incredible month-long competition. And while these top athletes are competing in South Africa, people around the globe are playing soccer in leagues, schools, or just for fun…

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Postmenopausal women who are at increased risk[1] of osteoporotic fractures should be treated with denosumab if treatment with currently available oral bisphosphonates is unsuitable, according to draft guidance published today (Friday 18 June) by NICE. Denosumab (Prolia, Amgen) is a newly-licensed treatment for women at increased risk of osteoporotic fractures, given by injection twice [...] Read more »

Italian postmenopausal women who have a low calcium intake show a higher risk of developing both osteoporosis and hypertension (a chronic medical condition in which arterial blood pressure is elevated) than those who consume higher levels of calcium according to research presented at EULAR 2010, the Annual Congress of the European League Against Rheumatism in [...] Read more »

The degradation of proteins and other macromolecules in cells is vital to survival. Disruption of this process can result in serious disease…

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In a medical emergency, a puncture of the cranium is commonly treated with an implant. While replacements made of titanium merely plug holes, a new kind of degradable implant stimulates the body to regenerate itself: It is a custom-fit and disappears to the same extent that the bone regrows. The body can heal minor bone [...] Read more »